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"Food choices study" led by Professor Theresa Marteau at the Behaviour and Health Research Unit. This study aims to improve our understanding of the factors that influence food choices and preferences in a normal range of adults. Volunteers will undertake a single computer based task lasting 20 to 30 minutes. This can be completed from their own computer. You can view the full information sheet sent to volunteers here.
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“Identification of biomarkers of the IFN signature” led by Professor John Todd, JDRF/Wellcome Trust Diabetes and Inflammation Laboratory. Our aim is to study IFIH1, responsible for sensing virus threats and generating interferon alpha, a powerful signalling molecule, in response to the infection, and how it contributes to type 1 diabetes. To do so, we will study Systemic Lupus Erythematosus (SLE), another autoimmune condition, where the same gene takes a major role, and where patients are known to have elevated levels of interferon alpha in circulation. We will measure the effects of interferon in gene expression and how this correlates with white blood cellular features. |
"Genes and mechanisms in clonal blood disorders" led by Professor Anthony Green at the University of Cambridge Department of Haematology. This study is investigating the way natural variation in genes affects the formation of blood cells, in order to better understand diseases of the blood system. Volunteers will be asked to provide a blood sample. The full information sheet sent to volunteers can be viewed here.
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“Online Food Shopping Study” led by Professor Theresa Marteau at the Behaviour and Health Research Unit. This study aims to improve our understanding of the factors that influence food purchasing. Volunteers who participate in this study will visit a ‘virtual online supermarket’ and complete a variety of shopping tasks.
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"A study of the long-term safety and mechanism of action of alemtuzumab (Campath-1H)" led by Dr Stephen Sawcer and Dr Alasdair Coles in the University of Cambridge Department of Clinical Neurosciences based at Addenbrooke's Hospital. A previous international study has identified genes potentially involved in multiple sclerosis. This study aims to investigate a number of these genes, confirming their role, defining the mechanisms involved and potentially identifying new treatment targets. Volunteers will be asked to give up a blood sample. The full information sheet sent to volunteers can be viewed here. |
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"PlAteletS in HeAlthy" individuals (PASHA) led by Professor Willem H. Ouwehand at the NHS Blood and Transplant. The overall goal of the PASHA study is to obtain a better understanding of the genetic and molecular mechanisms, which underlie the observed associations between common GWAS variants and the processes of megakaryopoiesis and platelet formation. In addition we would like to determine whether the GWAS SNVs also exert an effect on the prothrombotic function of platelets. Volunteers that take part in this study give a blood sample and the full information sheet sent to volunteers can be viewed here. |